{"id":584,"date":"2014-03-23T11:17:01","date_gmt":"2014-03-23T02:17:01","guid":{"rendered":"http:\/\/www.cns.atr.jp\/cbi\/?page_id=584"},"modified":"2023-11-17T11:38:13","modified_gmt":"2023-11-17T02:38:13","slug":"cortical_current_estimation","status":"publish","type":"page","link":"https:\/\/bicr.atr.jp\/cbi\/research\/cortical_current_estimation\/","title":{"rendered":"\u8907\u6570\u8133\u6d3b\u52d5\u8a08\u6e2c\u7d71\u5408\u306b\u3088\u308b\u9ad8\u6642\u7a7a\u9593\u8133\u6d3b\u52d5\u63a8\u5b9a\u6cd5"},"content":{"rendered":"<p><strong>\u3000\u8133\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u7814\u7a76\u306b\u306f\u3001\u30df\u30ea\u79d2\u306e\u30aa\u30fc\u30c0\u3067\u5909\u5316\u3059\u308b\u8133\u6d3b\u52d5\u3092\u8a08\u6e2c\u3059\u308b\u65b9\u6cd5\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u73fe\u5728\u306e\u3068\u3053\u308d\u305d\u308c\u3092\u6e80\u305f\u3059\u8a08\u6e2c\u65b9\u6cd5\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002MEG\u3084EEG\u306e\u3082\u3064\u6642\u9593\u5206\u89e3\u80fd\u306f\u30df\u30ea\u79d2\u306e\u30aa\u30fc\u30c0\u3067\u3059\u304c\u3001\u8133\u5185\u306e\u6d3b\u52d5\uff08\u3057\u3070\u3057\u3070\u96fb\u6d41\u6e90\u3068\u547c\u3070\u308c\u308b\uff09\u304c\u751f\u6210\u3059\u308b\u78c1\u5834\u307e\u305f\u306f\u96fb\u5834\u3092\u982d\u5916\u306b\u7f6e\u3044\u305f\u30bb\u30f3\u30b5\u3067\u8a08\u6e2c\u3059\u308b\u305f\u3081\u3001\u8133\u5185\u306b\u304a\u3051\u308b\u6d3b\u52d5\u4f4d\u7f6e\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u3002\u8133\u5185\u306e\u6d3b\u52d5\u4f4d\u7f6e\u3092\u77e5\u308b\u305f\u3081\u306b\u306f\u3001\u8a08\u6e2c\u30c7\u30fc\u30bf\u3068\u96fb\u78c1\u5834\u306e\u6cd5\u5247\u3092\u7528\u3044\u3066\u63a8\u5b9a\u3059\u308b\u554f\u984c\u300c\u96fb\u6d41\u6e90\u63a8\u5b9a\u554f\u984c\u300d\u3092\u89e3\u304b\u306a\u304f\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/strong><strong>\u300c\u96fb\u6d41\u6e90\u63a8\u5b9a\u554f\u984c\u300d<\/strong><strong>\u306f\u3001\u305f\u3068\u3048\u78c1\u5834\u3084\u96fb\u4f4d\u306e\u30c7\u30fc\u30bf\u306b\u30ce\u30a4\u30ba\u304c\u7121\u304f\u3066\u3082\u3001\u539f\u7406\u7684\u306b\u30c7\u30fc\u30bf\u3060\u3051\u304b\u3089\u8133\u5185\u6d3b\u52d5\u5206\u5e03\u3092\u4e00\u610f\u306b\u5b9a\u3081\u3089\u308c\u306a\u3044\u9006\u554f\u984c\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n<p>\u305d\u306e\u305f\u3081\u3001\u8a08\u6e2c\u30c7\u30fc\u30bf\u4ee5\u5916\u306e\u4e8b\u524d\u60c5\u5831\u3092\u52a0\u5473\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u521d\u671f\u306e\u89e3\u6cd5\u3067\u306f\u3001\u96fb\u6d41\u5f37\u5ea6\u306e\u6700\u5c0f\u5316\u3084\u7a7a\u9593\u7684\u306a\u6ed1\u3089\u304b\u3055\u306a\u3069\u96fb\u6d41\u6e90\u306e\u5b9a\u6027\u7684\u306b\u6e80\u305f\u3059\u3079\u304f\u6027\u8cea\u306b\u6ce8\u76ee\u3057\u305f\u4e8b\u524d\u60c5\u5831\u304c\u4f7f\u308f\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u5f8c\u3001\u3088\u308a\u5b9a\u91cf\u7684\u306a\u4e8b\u524d\u60c5\u5831\u3068\u3057\u3066fMRI\u30c7\u30fc\u30bf\u304c\u6301\u3064\u8133\u5185\u4f4d\u7f6e\u60c5\u5831\u3092\u5229\u7528\u3059\u308b\u65b9\u6cd5\u304c\u6ce8\u76ee\u3092\u6d74\u3073\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u672c\u7814\u7a76\u5ba4\u3067\u306f\u3001fMRI\u306e\u6301\u3064\u9ad8\u3044\u7a7a\u9593\u5b9a\u4f4d\u6027\u3092\u5229\u7528\u3057\u9ad8\u6642\u7a7a\u9593\u5206\u89e3\u80fd\u306a\u8133\u6d3b\u52d5\u63a8\u5b9a\u3092\u5b9f\u73fe\u3059\u308b\u3001\u968e\u5c64\u30d9\u30a4\u30ba\u30e2\u30c7\u30eb\u3068\u5909\u5206\u30d9\u30a4\u30ba\u6cd5\u3092\u7528\u3044\u305f\u96fb\u6d41\u6e90\u63a8\u5b9a\u6cd5\u3092\u8003\u6848\u3057\u307e\u3057\u305f(Sato et al. 2004)\u3002\uff08\u6ce8\u610f\uff09\u672c\u65b9\u6cd5\u3092\u7528\u3044\u308b\u306b\u306f\u3001\u540c\u4e00\u5b9f\u9a13\u6642\u306e\u8133\u6d3b\u52d5\u3092fMRI\u3068MEG\u30672\u56de\u8a08\u6e2c\u3057\u306a\u304f\u3066\u306f\u3044\u3051\u307e\u305b\u3093\u3002<\/p>\n<p>fMRI\u3067\u5f97\u3089\u308c\u308b\u7a7a\u9593\u60c5\u5831\u3092MEG\/EEG(\/\u306fMEG\u307e\u305f\u306fEEG\u306e\u610f\u5473)\u306e\u96fb\u6d41\u6e90\u63a8\u5b9a\u554f\u984c\u306b\u7d44\u307f\u8fbc\u3080\u65b9\u6cd5\u306f\u5927\u304d\u304f\u5206\u3051\u30662\u901a\u308a\u3042\u308a\u307e\u3059\u30021\u3064\u306f\u3001\u4e8b\u524d\u60c5\u5831\u3068\u3057\u3066\u53d6\u308a\u8fbc\u3080\u65b9\u6cd5\u3001\u3082\u3046\uff11\u3064\u306f\u751f\u6210\u30e2\u30c7\u30eb\u3068\u3057\u3066\u53d6\u308a\u8fbc\u3080\u65b9\u6cd5\u3067\u3059(ROSA et al. 2010)\u3002\u4e8b\u524d\u60c5\u5831\u3068\u3057\u3066\u53d6\u308a\u8fbc\u3080\u65b9\u6cd5\u306f\u3001fMRI\u3068\u96fb\u6d41\u6e90\u306e\u5bfe\u5fdc\u95a2\u4fc2\u3092\u6570\u5f0f\u7684\u306a\u95a2\u4fc2\u306e\u307f\u3067\u8a18\u8ff0\u3057\u307e\u3059\u3002\u4e00\u65b9\u3001\u751f\u6210\u30e2\u30c7\u30eb\u3092\u4f7f\u3046\u65b9\u6cd5\u306f\u3001\u96fb\u6d41\u6e90\u304b\u3089fMRI\u3078\u306e\u751f\u6210\u904e\u7a0b\u3001\u96fb\u6d41\u6e90\u304b\u3089MEG\/EEG\u306e\u751f\u6210\u904e\u7a0b\u3092\u30e2\u30c7\u30eb\u5316\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066fMRI\u306e\u60c5\u5831\u3092MEG\/EEG\u306e\u60c5\u5831\u3092\u7d44\u307f\u5408\u308f\u305b\u307e\u3059\u3002<\/p>\n<p>\u672c\u30b0\u30eb\u30fc\u30d7\u3067\u958b\u767a\u3057\u305f\u968e\u5c64\u30d9\u30a4\u30ba\u30e2\u30c7\u30eb(Sato et al. 2004)\u306f\u3001\u524d\u8005\u306e\u4e8b\u524d\u5206\u5e03\u3068\u3057\u3066fMRI\u60c5\u5831\u3092\u53d6\u308a\u8fbc\u3080\u65b9\u6cd5\u306b\u5c5e\u3057\u307e\u3059\u3002\u76f4\u89b3\u7684\u306b\u8a00\u3048\u3070\u3001fMRI\u30c7\u30fc\u30bf\u3092\u7d71\u8a08\u51e6\u7406\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u5f97\u305f\u201d\u6d3b\u52d5\u30de\u30c3\u30d7\u201d\u3092\u96fb\u6d41\u6e90\u306e\u7a7a\u9593\u7684\u914d\u7f6e\u3068\u3057\u3066\u5229\u7528\u3057\u3001\u6642\u9593\u5909\u5316\u3059\u308b\u6ce2\u5f62\u60c5\u5831\u3068\u3057\u3066MEG\/EEG\u30c7\u30fc\u30bf\u3092\u4f7f\u3046\u30a4\u30e1\u30fc\u30b8\u3067\u3059\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u96fb\u6d41\u6e90\u306e\u7a7a\u9593\u30d1\u30bf\u30fc\u30f3\u3092\u6c42\u3081\u305f\u3044\u672a\u77e5\u30d1\u30e9\u30e1\u30fc\u30bf\u3068\u3057\u3066\u3001\u96fb\u6d41\u6e90\u306e\u7a7a\u9593\u30d1\u30bf\u30fc\u30f3\u306e\u4e8b\u524d\u60c5\u5831\u3068\u3057\u3066fMRI\u6d3b\u52d5\u30de\u30c3\u30d7\u3092\u7d44\u307f\u8fbc\u307f\u3001\u96fb\u6d41\u6e90\u306e\u7a7a\u9593\u30d1\u30bf\u30fc\u30f3\u304b\u3089MEG\/EEG\u306e\u89b3\u6e2c\u904e\u7a0b\u3092\u5c24\u5ea6\u95a2\u6570\u3068\u3057\u3066\u78ba\u7387\u30e2\u30c7\u30eb\u3067\u5b9a\u5f0f\u5316\u3057\u307e\u3059\u3002\u63a8\u5b9a\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u4e8b\u5f8c\u5206\u5e03\u3092\u5909\u5206\u30d9\u30a4\u30ba\u6cd5\uff08variational Bayes; VB\uff09\u306b\u3088\u308a\u6c42\u3081\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u5c0e\u51fa\u3057\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-122\" title=\"hierarchical_bayes_estimation\" src=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/hierarchical_bayes_estimation.png\" alt=\"\" width=\"617\" height=\"486\" srcset=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/hierarchical_bayes_estimation.png 685w, https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/hierarchical_bayes_estimation-300x236.png 300w\" sizes=\"auto, (max-width: 617px) 100vw, 617px\" \/><\/p>\n<p>fMRI\u3092\u4e8b\u524d\u60c5\u5831\u3068\u3057\u3066\u53d6\u308a\u8fbc\u3080\u65b9\u6cd5\u306f\u5225\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u3082\u63d0\u6848\u3055\u308c\u3066\u3044\u307e\u3057\u305f(Liu et al. 1998; Dale et al. 2000)\u304c\u3001VBMEG\u306f\u968e\u5c64\u4e8b\u524d\u5206\u5e03\u3092\u7528\u3044\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u65e2\u5b58\u624b\u6cd5\u306e\u5f31\u70b9\u3092\u89e3\u6d88\u3057\u3066\u3044\u307e\u3059\u3002\u65e2\u5b58\u624b\u6cd5\u3067\u306f\u3001fMRI\u304cMEG\/EEG\u306e\u6d3b\u52d5\u5206\u5e03\u3068\u3057\u3066\u5b8c\u5168\u306b\u6b63\u78ba\u306a\u60c5\u5831\u3092\u4e0e\u3048\u308b\u3053\u3068\u3092\u524d\u63d0\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u524d\u63d0\u6761\u4ef6\u306f\u3001fMRI\u3068MEG\/EEG\u306e\u611f\u5ea6\u306e\u9055\u3044\u3001\u7d71\u8a08\u7684\u51e6\u7406\u306e\u8aa4\u5dee\u3001fMRI\u3068MEG\u5b9f\u9a13\u30d1\u30e9\u30c0\u30a4\u30e0\u306e\u5dee\u7570\u306a\u3069\u306e\u7406\u7531\u306b\u5fc5\u305a\u3057\u3082\u6e80\u305f\u3055\u308c\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u672c\u624b\u6cd5\u3067\u306f\u3001MEG\/EEG\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u3044\u3066fMRI\u60c5\u5831\u306e\u53d6\u308a\u8fbc\u3080\u5ea6\u5408\u3044\u3092\u5834\u6240\u3054\u3068\u306b\u8abf\u6574\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001fMRI\u3068MEG\/EEG\u306e\u6d3b\u52d5\u6e90\u306b\u76f8\u9055\u304c\u3042\u3063\u3066\u3082MEG\/EEG\u306e\u60c5\u5831\u3092\u3088\u308a\u91cd\u8996\u3057\u305f\u96fb\u6d41\u6e90\u63a8\u5b9a\u3092\u4e0e\u3048\u307e\u3059\u3002\u307e\u305f\u3001\u3082\u30461\u3064\u306e\u7279\u9577\u3068\u3057\u3066\u3001\u63a8\u5b9a\u3055\u308c\u308b\u96fb\u6d41\u6e90\u30d1\u30bf\u30fc\u30f3\u304c\u7a7a\u9593\u7684\u306b\u30b9\u30d1\u30fc\u30b9\u306b\u306a\u308a\u3001\u8133\u6d3b\u52d5\u306e\u5c40\u5728\u8ad6\u3068\u76f8\u6027\u306e\u826f\u3044\u63a8\u5b9a\u6cd5\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-123\" title=\"dipole_estimation\" src=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/dipole_estimation.png\" alt=\"\" width=\"617\" height=\"486\" srcset=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/dipole_estimation.png 685w, https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/dipole_estimation-300x236.png 300w\" sizes=\"auto, (max-width: 617px) 100vw, 617px\" \/><\/p>\n<p>VBMEG\u306f\u3001\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3060\u3051\u3067\u306a\u304f\u3001\u5b9f\u9a13\u30c7\u30fc\u30bf\uff08\u8996\u899a\u30fb\u4f53\u6027\u611f\u899a\u30fb\u8074\u899a\u30fb\u904b\u52d5\u5b9f\u9a13\u306a\u3069\uff09\u3067\u3082\u3001\u305d\u306e\u6709\u7528\u6027\u304c\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5b9f\u9a13\u8005\u306e\u65b9\u3005\u306b\u76f4\u89b3\u7684\u306b\u4f7f\u7528\u3057\u3066\u3082\u3089\u3046\u305f\u3081\u306eGUI\u4ed8\u304d\u306e\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u3068\u3057\u3066\u4e00\u822c\u516c\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u662f\u975e\u3001\u9ad8\u6642\u7a7a\u9593\u5206\u89e3\u80fd\u304c\u5fc5\u8981\u306a\u7814\u7a76\u3092\u884c\u308f\u308c\u3066\u3044\u308b\u65b9\u306f\u5229\u7528\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><a href=\"http:\/\/vbmeg.atr.jp\/?lang=ja\"> VBMEG\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u306e\u30da\u30fc\u30b8 <\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-124\" title=\"vbmeg\" src=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/vbmeg.png\" alt=\"\" width=\"628\" height=\"486\" srcset=\"https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/vbmeg.png 698w, https:\/\/bicr.atr.jp\/cbi\/wp-content\/uploads\/2010\/07\/vbmeg-300x232.png 300w\" sizes=\"auto, (max-width: 628px) 100vw, 628px\" \/><\/p>\n<h3>\u53c2\u8003\u6587\u732e<\/h3>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>Sato, M. et al., 2004. Hierarchical Bayesian estimation for MEG inverse problem. NeuroImage, 23(3), pp.806\u201326.<\/li>\n<li>Dale, A.M. et al., 2000. Dynamic statistical parametric mapping: combining fMRI and MEG for high-resolution imaging of cortical activity. Neuron, 26(1), pp.55\u201367.<\/li>\n<li>Liu, A.K., Belliveau, J.W. &amp; Dale, A.M., 1998. Spatiotemporal imaging of human brain activity using functional MRI constrained magnetoencephalography data: Monte Carlo simulations. Proceedings of the National Academy of Sciences of the United States of America, 95(15), pp.8945\u201350.<\/li>\n<li>Rosa, M.J., Daunizeau, J. &amp; Friston, K.J., 2010. EEG-fMRI Integration: A Critical Review of Biophysical Modeling and Data Analysis Approarches. Journal of Integrative Neuroscience, 09(04), pp.453\u2013476.<\/li>\n<li><a href=\"https:\/\/bicr.atr.jp\/cbi\/vbmeg\/reference.html\">VBMEG\u95a2\u9023\u306e\u8cc7\u6599<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u3000\u8133\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u7814\u7a76\u306b\u306f\u3001\u30df\u30ea\u79d2\u306e\u30aa\u30fc\u30c0\u3067\u5909\u5316\u3059\u308b\u8133\u6d3b\u52d5\u3092\u8a08\u6e2c\u3059\u308b\u65b9\u6cd5\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u73fe\u5728\u306e\u3068\u3053\u308d\u305d\u308c\u3092\u6e80\u305f\u3059\u8a08\u6e2c\u65b9\u6cd5\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002MEG\u3084EEG\u306e\u3082\u3064\u6642\u9593\u5206\u89e3\u80fd\u306f\u30df\u30ea\u79d2\u306e\u30aa\u30fc\u30c0\u3067\u3059\u304c\u3001\u8133\u5185\u306e\u6d3b\u52d5\uff08\u3057\u3070\u3057\u3070\u96fb\u6d41\u6e90\u3068\u547c\u3070\u308c [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":22,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-584","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/pages\/584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/comments?post=584"}],"version-history":[{"count":28,"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/pages\/584\/revisions"}],"predecessor-version":[{"id":1854,"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/pages\/584\/revisions\/1854"}],"up":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/pages\/22"}],"wp:attachment":[{"href":"https:\/\/bicr.atr.jp\/cbi\/wp-json\/wp\/v2\/media?parent=584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}