\u6982\u8981
\nPatients with ALS or stroke, sometimes go into a total locked-in state. In this state, they can not move their muscles at all even when they are clearly thinking what they want to do. Brain-machine interface, or BMI, is one of the ways to improve their quality of life. The BMI infers the patient\u2019s will only using their brain signals and translates them to control some external devices, such as prosthetic hand.
\nIn this study, we succeeded to develop an integrated system to control a prosthetic hand using human electrocorticograms in real-time. Notably, this new system was applied to a post-stroke patient with surprisingly good results. We found that the patient\u2019s hand movements were correctly detected and inferred only by using the electrocroticographic signals recorded on the patient\u2019s sensorimotor cortex. Actually, the prosthetic hand was able to mimic the patient\u2019s movements in real-time. This is the first report describing the use of the electrocorticographic signals to control the prosthetic hand. Because the signals are known to be stable and durable signals for the clinically feasible BMI systems, this success paves the way for the motor restoration of paralyzed patients with using the BMI in daily clinical practice. <\/p>\n
\u9ad8\u4f4d\u810a\u9ac4\u640d\u50b7\u3084\u91cd\u75c7\u306e\u7b4b\u59d4\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u60a3\u8005\u3067\u306f\u8eab\u4f53\u304a\u3088\u3073\u9854\u9762\u306e\u904b\u52d5\u306f\u3082\u3068\u3088\u308a\u610f\u601d\u8868\u793a\u3082\u5168\u304f\u3067\u304d\u305a\uff08total locked-in\uff09\u3001\u60b2\u60e8\u306a\u72b6\u6cc1\u306b\u7f6e\u304b\u308c\u3066\u3044\u308b\u3002Brain machine interface (BMI)\u6280\u8853\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u56db\u80a2\u9ebb\u75fa\u60a3\u8005\u304c\u5ff5\u3058\u308b\u3060\u3051\u3067\u5916\u90e8\u88c5\u7f6e\uff08\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u3001\u30d9\u30c3\u30c9\u3084\u7167\u660e\u306a\u3069\u306e\u74b0\u5883\u5236\u5fa1\u6a5f\u5668\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u88dc\u52a9\u88c5\u7f6e\u3001\u30ed\u30dc\u30c3\u30c8\u30cf\u30f3\u30c9\uff08\u96fb\u52d5\u7fa9\u624b\uff09\u7b49\uff09\u3092\u64cd\u4f5c\u3067\u304d\u308b\u3088\u3046\u306a\u3001\u610f\u601d\u4f1d\u9054\u3084\u904b\u52d5\u6a5f\u80fd\u306e\u518d\u5efa\u304c\u671f\u5f85\u3055\u308c\u308b\u3002\u5927\u962a\u5927\u5b66\u8133\u795e\u7d4c\u5916\u79d1\u306e\u67f3\u6fa4\u7422\u53f2\uff08\u8133\u795e\u7d4c\u5916\u79d1\/ATR\u975e\u5e38\u52e4\u7814\u7a76\u54e1\uff09\u3001\u5e73\u7530\u96c5\u4e4b\uff08\u8133\u795e\u7d4c\u5916\u79d1\/GCOE\u7279\u4efb\u51c6\u6559\u6388\uff09\u7b49\u306f\u56fd\u969b\u96fb\u6c17\u901a\u4fe1\u57fa\u790e\u6280\u8853\u7814\u7a76\u6240\uff08ATR\uff09\u8133\u60c5\u5831\u7814\u7a76\u6240\u30fb\u795e\u7d4c\u60c5\u5831\u5b66\u7814\u7a76\u5ba4\u306e\u795e\u8c37\u4e4b\u5eb7\u5ba4\u9577\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u3068\u5171\u540c\u3067\u3001\u30d2\u30c8\u306e\u8133\u8868\u304b\u3089\u8a08\u6e2c\u3057\u305f\u8133\u6ce2\uff08\u76ae\u8cea\u8133\u6ce2\uff09\u3092\u7528\u3044\u305fBMI\u306e\u958b\u767a\u3092\u884c\u3063\u3066\u3044\u308b\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u30d2\u30c8\u306e\u611f\u899a\u904b\u52d5\u91ce\u3088\u308a\u5f97\u305f\u76ae\u8cea\u8133\u6ce2\u3092\u7528\u3044\u3066\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306b\u96fb\u52d5\u7fa9\u624b\u3092\u5236\u5fa1\u3057\u305f\u4e16\u754c\u3067\u521d\u3081\u3066\u306e\u6210\u679c\u3067\u3042\u308b\u3002\uff08\u56f31\u3001\u30d3\u30c7\u30aa\u53c2\u7167\uff09\u3002<\/p>\n
BMI\u306b\u7528\u3044\u308b\u8133\u4fe1\u53f7\u306f\u69d8\u3005\u3067\u3042\u308b\u304c\u3001\u904b\u52d5\u306b\u95a2\u3059\u308b\u8133\u304b\u3089\u306e\u6700\u7d42\u51fa\u529b\u90e8\u3067\u3042\u308b\u4e00\u6b21\u904b\u52d5\u91ce\u306e\u76ae\u8cea\u8133\u6ce2\uff08Electrocorticogram: ECoG\uff09\u306f\u3001\u4fe1\u53f7\u306e\u5b89\u5b9a\u6027\u3084\u5f97\u3089\u308c\u308b\u60c5\u5831\u91cf\u306a\u3069\u306e\u70b9\u3067\u5b9f\u7528\u7684\u306aBMI\u306b\u6709\u5229\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u5b9f\u969b\u3001\u3066\u3093\u304b\u3093\u624b\u8853\u306a\u3069\u3067\u982d\u84cb\u5185\u306b\u96fb\u6975\u3092\u7559\u7f6e\u3057\u305f\u60a3\u8005\u304b\u3089\u611f\u899a\u904b\u52d5\u91ce\u306e\u76ae\u8cea\u8133\u6ce2\u3092\u8a08\u6e2c\u3057\u3001\u3053\u308c\u3092\u7528\u3044\u3066PC\u306e\u30ab\u30fc\u30bd\u30eb\u3092\u5236\u5fa1\u3059\u308b\u6280\u8853\u306a\u3069\u304c\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u5b9f\u969b\u306e\u81e8\u5e8a\u3067BMI\u3092\u5fc5\u8981\u3068\u3059\u308b\u9ad8\u9f62\u8005\u306e\u4e2d\u306b\u306f\u3001PC\u64cd\u4f5c\u306b\u4e0d\u6163\u308c\u306a\u60a3\u8005\u3082\u591a\u304f\u3001\u601d\u3063\u305f\u901a\u308a\u306b\u5236\u5fa1\u3067\u304d\u308b\u4e0a\u80a2\u3092\u518d\u5efa\u3059\u308b\u3053\u3068\u306f\u60a3\u8005\u306eADL\u6539\u5584\u306b\u91cd\u8981\u3067\u3042\u308b\u3002\u305d\u3053\u3067\u6211\u3005\u306f\u76ae\u8cea\u8133\u6ce2\u3092\u7528\u3044\u3066\u601d\u3063\u305f\u901a\u308a\u306b\u5236\u5fa1\u3067\u304d\u308b\u96fb\u52d5\u7fa9\u624b\u306e\u958b\u767a\u3092\u884c\u3063\u305f\u3002<\/p>\n
\u672c\u7814\u7a76\u3067\u306f\u3001\u611f\u899a\u904b\u52d5\u91ce\u306b\u96fb\u6975\u3092\u7559\u7f6e\u3057\u305f\u60a3\u8005\uff08\u96e3\u6cbb\u6027\u75bc\u75db\uff0a\uff11\u306b\u5bfe\u3059\u308b\u904b\u52d5\u91ce\u523a\u6fc0\u7642\u6cd5\uff0a\uff12\uff09\u306b\u5354\u529b\u3057\u3066\u9802\u304d\u3001\u60a3\u8005\u304c\u30b0\u30fc\u30c1\u30e7\u30ad\u30d1\u30fc\u306e3\u7a2e\u985e\u306e\u904b\u52d5\u3092\u884c\u3046\u969b\u306e\u76ae\u8cea\u8133\u6ce2\u3092\u8a08\u6e2c\u3057\u305f\u3002\u3053\u308c\u3092\u3001support vector machine(SVM) \u3068\u3044\u3046\u65b9\u6cd5\u3067\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u304c\u5b66\u7fd2\u3057\u3001\u60a3\u8005\u304c\u3069\u306e\u904b\u52d5\u3092\u884c\u3063\u305f\u304b\u3001\u60a3\u8005\u304c\u3044\u3064\u904b\u52d5\u3092\u884c\u3046\u304b\u3092\u904b\u52d51\u56de\u6bce\u306e\u76ae\u8cea\u8133\u6ce2\u3060\u3051\u304b\u3089\u63a8\u5b9a\u3057\u305f\u3002\u3053\u306e\u63a8\u5b9a\u7d50\u679c\u306b\u57fa\u3065\u3044\u3066\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306b\u96fb\u52d5\u7fa9\u624b\u3092\u5236\u5fa1\u3057\u305f\u3002\u3053\u306e\u5236\u5fa1\u30b7\u30b9\u30c6\u30e0\u306f200ms\u306e\u7cbe\u5ea6\u3067\u30d2\u30c8\u306e\u4e0a\u80a2\u904b\u52d5\u3092\u63a8\u5b9a\u3057\u5373\u5ea7\u306b\u96fb\u52d5\u7fa9\u624b\u306e\u904b\u52d5\u3092\u5b9f\u73fe\u3059\u308b\u4e8b\u306b\u6210\u529f\u3057\u305f\u3002<\/p>\n
\u56f3\uff11\uff1a\u76ae\u8cea\u8133\u6ce2\u306b\u3088\u308b\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u96fb\u52d5\u7fa9\u624b\u5236\u5fa1
\n\u8efd\u5ea6\u9ebb\u75fa\u60a3\u8005\u306e\u76ae\u8cea\u8133\u6ce2\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306b\u89e3\u6790\u3057power spectrum\u306e\u5909\u5316\u304b\u3089\u904b\u52d5\u306e\u958b\u59cb\u6642\u70b9\u3068\u904b\u52d5\u5185\u5bb9\u3092\u63a8\u5b9a\u3057\u3001\u5373\u5ea7\u306b\u96fb\u52d5\u7fa9\u624b\u306e\u904b\u52d5\u3068\u3057\u3066\u5b9f\u73fe\u3057\u305f\u3002<\/p>\n
\uff0a\uff11\uff1a\u96e3\u6cbb\u6027\u75bc\u75db\uff1a\u3000\u8133\u5352\u4e2d\u5f8c\u3084\u56db\u80a2\u306e\u5207\u65ad\u5f8c\u306b\u751f\u3058\u308b\u6fc0\u75db\u3067\u3001\u85ac\u7269\u7642\u6cd5\u306a\u3069\u4e00\u822c\u7684\u306a\u75bc\u75db\u6cbb\u7642\u3067\u306f\u75db\u307f\u304c\u8efd\u5feb\u3057\u306a\u3044\u3082\u306e\u3002
\n\uff0a\uff12\uff1a\u904b\u52d5\u91ce\u523a\u6fc0\u7642\u6cd5\uff1a\u3000\u5927\u8133\u76ae\u8cea\u4e00\u6b21\u904b\u52d5\u91ce\u3092\u96fb\u6c17\u523a\u6fc0\u3059\u308b\u3053\u3068\u3067\u3001\u96e3\u6cbb\u6027\u75bc\u75db\u3092\u8efd\u6e1b\u3059\u308b\u6cbb\u7642\u6cd5\u3002\u8133\u8868\u306b\u96fb\u6975\u3092\u7559\u7f6e\u3057\u3066\u76f4\u63a5\u3001\u8133\u8868\u3092\u96fb\u6c17\u523a\u6fc0\u3059\u308b\u3002<\/p>\n
\u8ad6\u6587\u8457\u8005\u540d\u3068\u30bf\u30a4\u30c8\u30eb
\nTakufumi Yanagisawa, Masayuki Hirata, Youichi Saitoh, Tetsu Goto, Haruhiko Kishima, Ryohei Fukuma, Hiroshi Yokoi, Yukiyasu Kamitani, Toshiki Yoshimine<\/p>\n
\u201cReal-time control of a prosthetic hand using human electrocorticograms\u201d<\/p>\n
\u7814\u7a76\u5b9f\u65bd\u6a5f\u95a2
\n\u5927\u962a\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1\u8133\u795e\u7d4c\u5916\u79d1
\n\t\u67f3\u6fa4\u7422\u53f2\u3001\u5e73\u7530\u96c5\u4e4b\u3001\u9f4b\u85e4\u6d0b\u4e00\u3001\u5f8c\u85e4\u54f2\u3001\u8cb4\u5cf6\u6674\u5f66\u3001\u5409\u5cf0\u4fca\u6a39
\n(\u682a)\u56fd\u969b\u96fb\u6c17\u901a\u4fe1\u57fa\u790e\u6280\u8853\u7814\u7a76\u6240\uff08ATR\uff09\u8133\u60c5\u5831\u7814\u7a76\u6240
\n\t\u798f\u9593\u826f\u5e73\u3001\u795e\u8c37\u4e4b\u5eb7
\n\u6771\u4eac\u5927\u5b66\u5de5\u5b66\u90e8\u7cbe\u5bc6\u5de5\u5b66\u79d1
\n\t\u6a2a\u4e95\u6d69\u53f2<\/p>\n
\u554f\u3044\u5408\u308f\u305b\u5148
\n\u5927\u962a\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1\u8133\u795e\u7d4c\u5916\u79d1\u3000\u67f3\u6fa4\u7422\u53f2
\n\u3012565-0871 \u5927\u962a\u5e9c\u5439\u7530\u5e02\u5c71\u7530\u4e182-2
\n\u96fb\u8a71\uff1a06-6879-3652, FAX: 06-6879-3659
\nhttp:\/\/www.nsurg.med.osaka-u.ac.jp\/<\/p>\n","protected":false},"excerpt":{"rendered":"
\u6982\u8981 Patients with ALS or stroke, sometimes go into a total locked-in state. In this state, they can not move th […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":76,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1236","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/pages\/1236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/comments?post=1236"}],"version-history":[{"count":2,"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/pages\/1236\/revisions"}],"predecessor-version":[{"id":1238,"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/pages\/1236\/revisions\/1238"}],"up":[{"embeddable":true,"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/pages\/76"}],"wp:attachment":[{"href":"https:\/\/bicr.atr.jp\/dni\/wp-json\/wp\/v2\/media?parent=1236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}