1996
Society for Neuroscience 26th Annual Meeting (Washington D.C., U.S.A.)

A FUNCTIONAL MRI STUDY ON INTERNAL MODELS OF DYNAMIC TRANSFORMATIONS DURING LEARNING A VISUOMOTOR TASK.
H. Imamizu*1, S. Miyauchi2, Y. Sasaki2, R. Takino2, B. Putz2, and M. Kawato1 1   1ATR Human Information Processing Research Labs., Kyoto, Japan; 2Communications Research Labs., Tokyo, Jap

 
Some recent computational studies have stated that the central nervous system (CNS) acquires internal models of the kinematics and/or dynamics of controlled objects and environments for rapid and smooth control (e.g. Kawato & Gomi, 1992, TINS, 15, pp. 445-453). However, it is still unclear as to which part of the CNS is involved in acquiring these models during the control of visually guided limb movements. Using fMRI (1.5T, Siemens VISION, echo planar imaging) we examined cortical and subcortical activity in normal human subjects learning a visuomotor task under the dynamic alteration of visual feedback of the hand position. The task for the subjects was to move a computer mouse so that the cursor follows the target moving on the screen as closely as possible (a modification of the task used in Flament et al. 1994, Soc. Neuosci. Abst. p. 20). The position of the cursor was altered by a dynamic transformation of the mouse movement, namely integration of the previous mouse positions, in learning periods whereas no transformation was imposed in control periods. The errors, measured by taking a distance between the cursor and the target, decreased with practice in the learning period. Images (8-10 slices, 7-10 mm thick, through the cerebellum, occipital, parietal and part of the frontal lobes) scanned in both periods were compared with cross correlation. We found that the MR signal intensity in the biventer lobule of the cerebellum and parietal areas 5 and 7 was significantly higher in the learning period. The results suggest that these areas are involved in error correction by comparing visual information and kinesthetic information and in acquiring the internal models of the imposed dynamic transformation

 

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